Process for the manufacture of idalopirdine via hydrogenation of an imine

Process for the manufacture of idalopirdine via hydrogenation of an imine

The present invention relates to the preparation of N-(2-(6-fluoro-1H-indol-3-yl)-ethyl)- 3-(2,2,3,3-tetrafluoropropoxy)-benzylamine (Compound I), INN-name idalopirdine, and pharmaceutically acceptable salts thereof: Compound (I).

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Bibliographische Detailangaben
Hauptverfasser: Jacobsen, Mikkel Fog, Huber, Florian Anton Martin
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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Beschreibung
Zusammenfassung:The present invention relates to the preparation of N-(2-(6-fluoro-1H-indol-3-yl)-ethyl)- 3-(2,2,3,3-tetrafluoropropoxy)-benzylamine (Compound I), INN-name idalopirdine, and pharmaceutically acceptable salts thereof: Compound (I).