Combination therapy using dual inhibitor of c-MET and EGFR and IGF-1R inhibitor

Combination therapy using dual inhibitor of c-MET and EGFR and IGF-1R inhibitor

A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met and EGFR (hereinafter, 'c-Met/EGFR dual inhibitor') and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met/EGFR dual inhi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jimin, Kim, Bo Gyou, Lin, Powei, Lee, Saet Byoul, Oh, Seungja, Kim, Kyung Ah
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Beschreibung
Zusammenfassung:A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met and EGFR (hereinafter, 'c-Met/EGFR dual inhibitor') and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met/EGFR dual inhibitor.