Catheter assembly with reusable valve

A catheter assembly includes a catheter hub having an elastomeric septum that divides the catheter hub into a distal chamber and a proximal chamber. The septum also includes at least one slit that is closed and sealed when the septum is in an at-rest state. A septum activator is proximal the septum. When an external force pushes the activator against the septum, the activator deforms the septum so as to break the seal and create a flow path through the septum. A portion of the septum activator can be collapsible when subjected to the outside force. When the outside force is removed, the collapsible portion springs back to its at-rest shape, helping to pull the activator out of deforming engagement with the septum so that the septum can reseal. The activator can also be spring-biased away from engagement with the septum so that when the outside force is removed, the spring urges the activator out of engagement with the septum. With the activator removed, the septum slit can reseal.