Alkene production

The present invention provides a microbial cell capable of producing at least one terminal alkene from at least one short chain fatty acid, wherein the cell is genetically modified to comprise - at least a first genetic mutation that increases the expression relative to the wild type cell of an enzy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Haas Thomas, Dennig Alexander, Thiessenhusen Anja, Gilch Stefan, Buelter Thomas, Faber Kurt, Hall Melanie
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a microbial cell capable of producing at least one terminal alkene from at least one short chain fatty acid, wherein the cell is genetically modified to comprise - at least a first genetic mutation that increases the expression relative to the wild type cell of an enzyme (E 1 ) selected from the CYP152 peroxygenase family, and - at least a second genetic mutation that increases the expression relative to the wild type cell of at least one NAD(P)+ oxidoreductase (E 2 ) and the corresponding mediator protein, wherein the short chain fatty acid is a C4- C10 fatty acid.