Method of purifying an antibody

A method of purifying an antibody composition comprises application of anion exchange chromatography late in the purification process. An ultrafiltration/diafiltration-purified antibody composition is subjected to anion exchange chromatography (AEX) to form a pharmaceutically-pure antibody compositi...

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Hauptverfasser: Wijk-Basten Van Everdina Josephina Wilhelmina, Marzá Pérez Maria, Beijer De Thomas Antonius Bernardus, Eppink Michel Hendrikus Maria, Kokke Bastiaan Pieter Arjan
Format: Patent
Sprache:eng
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Zusammenfassung:A method of purifying an antibody composition comprises application of anion exchange chromatography late in the purification process. An ultrafiltration/diafiltration-purified antibody composition is subjected to anion exchange chromatography (AEX) to form a pharmaceutically-pure antibody composition.