Antibodies capable of binding to the coagulation Factor XI and/or its activated form factor Xia and uses thereof

Antibodies capable of binding to the coagulation Factor XI and/or its activated form factor Xia and uses thereof

The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.

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Bibliographische Detailangaben
Hauptverfasser: Gerdes Christoph, Dittmer Frank, Buchmüller Anja, Straβburger Julia, Leung Philberta, Grudzinska-Goebel Joanna, Finnern Ricarda, Jöriβen Hannah, Itakura Asako, Tucker Erik, Strerath Michael, Schäfer Martina, Wilmen Andreas
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.