Systems, methods and devices for acquiring and processing physiological signals

A system, method and device are described for biometric analysis using a wearable device. The device can be removeably securable to a user's skin surface and can include a plurality of electrodes positioned to acquire electrical signals from the skin surface. The device can also include an electromyography acquisition module and skin impedance acquisition module. A processing unit can use the electrodes to capture a plurality of electrical signals including at least one electromyography signal. The processing unit can generate calibration data based on a subset of the captured electrical signals and process the electromyography signals using the calibration data to determine a biometric for the user.