Orally disintegrating tablet containing bitterness-masking granules

Disclosed is a tablet containing anhydrous calcium hydrogen phosphate, granules (A) which contain sugars, and granules (B) which contain nuclear particles having a diameter of 10-500μm, medicine and a film coating, and which have a particle diameter of 700μm or less. The present invention enables ta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Obae Kazuhiro, Yoshida Naoya
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed is a tablet containing anhydrous calcium hydrogen phosphate, granules (A) which contain sugars, and granules (B) which contain nuclear particles having a diameter of 10-500μm, medicine and a film coating, and which have a particle diameter of 700μm or less. The present invention enables tablet-making difficulties during the manufacture of the tablet to be suppressed. In addition, the tablet has an appropriate hardness, an excellent disintegration time, and feels very good to ingest.