Purine inhibitors of human phosphatidylinositol 3-kinase delta

Purine inhibitors of human phosphatidylinositol 3-kinase delta

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser: Anthony Neville John, Altman Michael D, Zhou Hua, Fradera Llinas Francesc Xavier, Kattar Solomon, Zhang Rong, McGowan Meredeth, Katz Jason D, Deng Yongqi, Christopher Matthew P, Leng Xiansheng, Achab Abdelghani Abe, Methot Joey L, Zhang Sixing, Fong Kin Chiu, Mu Changwei, Garcia Yudith, Guzi Timothy
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.