Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds

Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds

The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating...

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Bibliographische Detailangaben
Hauptverfasser: Lupi Vittoria, Cohen Robert L, Caruso Michele, Perego Rita, Spencer Susan D, Flygare John A, Polakis Paul, Beria Italo, Valsasina Barbara, Polson Andrew, Salsa Matteo
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.