Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide

A novel polypeptide which has an excellent angiogenesis-inducing activity and an excellent antibacterial activity, and a novel angiogenesis-inducing agent which contains the polypeptide as an effective ingredient or a novel agent for treating a wound(s) which contains the polypeptide as an effective...

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Hauptverfasser: Morishita Ryuichi, Tomioka Hideki, Maeda Akito, Kanamori Toshihide, Saito Yoshimi, Komaba Shintaro, Tamura Nao, Gemba Takefumi, Sata Ryoko, Tenma Akiko
Format: Patent
Sprache:eng
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Zusammenfassung:A novel polypeptide which has an excellent angiogenesis-inducing activity and an excellent antibacterial activity, and a novel angiogenesis-inducing agent which contains the polypeptide as an effective ingredient or a novel agent for treating a wound(s) which contains the polypeptide as an effective ingredient are disclosed. The polypeptide of the present invention is a polypeptide whose amino acid sequence is shown in any one of SEQ ID NOs:1 to 6, 8 and 10. The angiogenesis-inducing agent which contains the polypeptide of the present invention as an effective ingredient is useful for the prevention, amelioration or treatment of a disease such as a burns, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliteran.