Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound

Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound

Methods of treating postherpetic neuralgia in a mammal with a pharmaceutical composition comprising a spiro-oxindole compound of the formula: are disclosed. The methods provide excellent penetration of the spiro-oxindole compound into the affected skin area to effectively reduce the severity of the...

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Bibliographische Detailangaben
Hauptverfasser: Malamut Richard, Price Nicola Anne, Goldberg Yigal Paul, Spiegelstein Ofer, Fetell Michael, Lamson Michael J
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Methods of treating postherpetic neuralgia in a mammal with a pharmaceutical composition comprising a spiro-oxindole compound of the formula: are disclosed. The methods provide excellent penetration of the spiro-oxindole compound into the affected skin area to effectively reduce the severity of the postherpetic neuralgia and/or to alleviate the postherpetic neuralgia with minimal or negligible systemic exposure of the spiro-oxindole compound.