Anti-carbamylated protein antibodies and the risk for arthritis

Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-CarP) for the cl...

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Hauptverfasser: van Veelen Petrus Antonius, Cerami Anthony, Shi Jing, Huizinga Thomas Willem Johannes, Toes Reinaldus Everardus Maria, Trouw Leendert Adrianus
Format: Patent
Sprache:eng
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Zusammenfassung:Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-CarP) for the classification of individuals suffering from, or at risk of suffering from, arthritis.