Method and topical formulation for treating localized edema

Methods and formulations are provided for the treatment of localized edema, particularly localized edema resulting from chronic venous insufficiency. A metal ion sequestrant is topically administered to a subject afflicted with localized edema in combination with a permeation enhancer selected from...

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Bibliographische Detailangaben
Hauptverfasser: Bhushan Rajiv, Goswamy Amit, Gin Jerry B
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods and formulations are provided for the treatment of localized edema, particularly localized edema resulting from chronic venous insufficiency. A metal ion sequestrant is topically administered to a subject afflicted with localized edema in combination with a permeation enhancer selected from methylsulfonylmethane and a combination of methylsulfonylmethane and dimethylsulfoxide. Topically administrable formulations for use in the aforementioned method are also provided.