Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same

Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same

Novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities are provided. A tricyclic heterocyclic compound represented by the formula (I a ): wherein the rings A a and B a , X a , Y a , R 1a , R 2a , R 3a , L 1a , L 2a , L 3a and n a are as defined in the...

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Hauptverfasser: Nasu Mariko, Watanabe Tsuneo, Kamon Junji, Minami Masataka, Hayashi Keishi, Uni Miyuki, Toyama Koji
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities are provided. A tricyclic heterocyclic compound represented by the formula (I a ): wherein the rings A a and B a , X a , Y a , R 1a , R 2a , R 3a , L 1a , L 2a , L 3a and n a are as defined in the description.