Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the tr...
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| creator | Turner Sean Colm Hornberger Wilfried Mack Helmut Hoft Carolin van Gaalen Marcel Bakker Margaretha Henrica Maria |
| description | The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the treatment of a medical disorder susceptible to the treatment with a compound that modulates, preferably inhibits, the activity of glycogen synthase kinase 3 , and methods of treatment of medical disorders susceptible to treatment with a compound that modulates glycogen synthase kinase 3 activity using the compounds. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
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