Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors

The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Turner Sean Colm, Hornberger Wilfried, Mack Helmut, Hoft Carolin, van Gaalen Marcel, Bakker Margaretha Henrica Maria
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the treatment of a medical disorder susceptible to the treatment with a compound that modulates, preferably inhibits, the activity of glycogen synthase kinase 3 , and methods of treatment of medical disorders susceptible to treatment with a compound that modulates glycogen synthase kinase 3 activity using the compounds.