Method for preparing 5-amino-benzoyl-benzofuran derivatives

The invention relates to a method for preparing 5-amino-benzoyl-benzofuran derivatives having the general formula in which R1 is hydrogen or an alkyl or aryl group and R2 is hydrogen, an alkyl, alkoxy or dialkylaminoalkoxy group. According to the invention, the compounds having formula I are prepare...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vayron Philippe, Bon Xavier, Delepine Jean-Louis, Largeau Denis, Jourdin Laure
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a method for preparing 5-amino-benzoyl-benzofuran derivatives having the general formula in which R1 is hydrogen or an alkyl or aryl group and R2 is hydrogen, an alkyl, alkoxy or dialkylaminoalkoxy group. According to the invention, the compounds having formula I are prepared by hydrogenating a 5-nitro-benzofuran derivative having the general formula in which R1 and R2 have the same meaning as above in the presence of palladized charcoal as a catalyst and in an ether or a mixture of ether as a solvent, thus forming the desired compounds.