Acyclic cyanoethylpyrazoles as janus kinase inhibitors

Acyclic cyanoethylpyrazoles as janus kinase inhibitors

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser: Young Jonathan R, Zhang Hongjun, Jung Joon, Close Joshua T, Martinez Michelle, White Catherine, Wilson Kevin, Brubaker Jason
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.