RNAi inhibition of alpha-ENaC expression

The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.

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Bibliographische Detailangaben
Hauptverfasser: Danahay Henry Luke, Hickman Emma, Vornlocher Hans-Peter, Geick Anke, Van Heeke Gino, Tan Pamela
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.