Method for optimising local drug delivery

The present invention relates to a data processing method for determining an infusion location in an anatomical region of interest of a patient's body for infusing a medical substance, the method being executed by a computer and comprising steps of: a) acquiring permeability data comprising information about the permeability of anatomical vessels in the body; b) acquiring body vessels set data comprising information about a body vessel set, wherein the body vessel set represents a set of at least one anatomical body vessel in the patient's body and wherein the body vessel set data comprises information about the spatial structure of the at least one body vessel; c) acquiring coverage condition data comprising information about a predetermined coverage of a target region with the medical substance; d) determining, for a plurality of candidate infusion locations, candidate coverage data comprising information about a candidate coverage of a target region with the medical substance based on the permeability data, the body vessel set data and the coverage condition data; e) determining infusion location data comprising information about the infusion location based on the permeability data, the body vessel set data and the coverage condition data.