System and method for increasing tolerance to fuel variation

A fuel control system for a multiple fuel internal combustion engine may include at least one cylinder pressure sensor associated with each cylinder of the engine. A data collection module may be configured to receive real-time cylinder pressure measurements from each of the at least one cylinder pressure sensors and calculate one or more actual combustion parameter values from the real-time cylinder pressure measurements. A comparison module may be configured to receive the calculated one or more actual combustion parameter values from the data collection module and compare the calculated one or more actual combustion parameter values for each cylinder to theoretical combustion parameter values to determine any difference therebetween, wherein the theoretical combustion parameter values are derived independently from any actual combustion parameter values based on real-time sensor measurements. A process control module may be configured to control fuel injection of at least two different types of fuel supplied to each cylinder in order to reduce any difference between the calculated actual combustion parameter values for each cylinder and the theoretical combustion parameter values.