2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as FAK/Pyk2 inhibitors

The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment...

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Hauptverfasser: Xu Xinhe, Xiao Dengming, Shen Yu, Tang Jia, Li Gen, Cheng Liang, Hu Yuandong, Wang Yin, Liu Xijie, Yu Honghao, Wu Wei, Zhang Lipeng, Wang Shulong, Li Chonglong, Liu Zhihua, Zhao Sheng
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/or Pyk2 mediated disorder or disease.