Vectors for molecule delivery to CD11b expressing cells

The invention relates to a novel use of a Bordetella adenylcyclase toxin in the manufacturing of vectors for targeting in vivo a molecule of interest, specifically to CD11b expressing cells. The invention also relates to an immunogenic composition that primes immune responses, to pharmaceutical comp...

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Bibliographische Detailangaben
Hauptverfasser: BAUCHE CECILE, LECLERC CLAUDE, KHELEF NADIA, EL-AZAMI EL-IDRISSI MOHAMMED, LADANT DANIEL, GUISO NICOLE, FAYOLLE CATHERINE, GUERMONPREZ PIERRE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a novel use of a Bordetella adenylcyclase toxin in the manufacturing of vectors for targeting in vivo a molecule of interest, specifically to CD11b expressing cells. The invention also relates to an immunogenic composition that primes immune responses, to pharmaceutical compositions and to a new vector for molecule delivery to CD11b expressing cells.