Immobilized proteins and methods and uses thereof

The invention relates to the field of covalently attaching proteins to a substrate, particularly to methods of immobilizing proteins by posttranslationally modifying a cysteine residue of said protein through the addition of functional groups. The invention also relates to biological molecules used...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAUCHET CECILE, POULTER CHARLES DALE, LABADI GUILLERMO ROBERTO, HAWKINS BOHATY ROCHELLE FRANCES
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:The invention relates to the field of covalently attaching proteins to a substrate, particularly to methods of immobilizing proteins by posttranslationally modifying a cysteine residue of said protein through the addition of functional groups. The invention also relates to biological molecules used in such techniques, including proteins, and detection methods and kits that utilize such immobilized proteins, such as a microdevice or "protein chip", a high-throughput screening device, and for the microscopy of proteins on a surface.