Method for the synthesis of a bifunctional complex

Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more rea...

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Hauptverfasser: OLSEN EVA KAMPMANN, SCHRØDER GLAD SANNE, FRESKGARD PER-OLA, GOULIAEV ALEX HAAHR, LUNDORF MIKKEL DYBRO, JENSEN KIM BIRKEBAEK, JAKOBSEN SOEREN NYBOE, PEDERSEN HENRIK, HOLTMANN ANETTE, SAMS CHRISTIAN KLARNER, FRANCH THOMAS, FELDING JAKOB
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more reactants, and provided with respective tag(s) identifying the reactant(s) at the priming site is using one or more enzymes.