Process for preparation of roflumilast

The present invention provides novel processes for the preparation of N-substituted benzamides having the formula VIc: In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHEN YI-JING, CHU GUO-DONG, PIKUL STANISLAW, KUO SHENUN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides novel processes for the preparation of N-substituted benzamides having the formula VIc: In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synthesis of roflumilast, are also provided.