Compounds that are ERK inhibitors

Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0).

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Hauptverfasser: WITTER DAVID J, O'BOYLE BRENDAN, FERGUSON RON, KURUKULASURIYA RAVI, BOYCE CHRISTOPHER, SLOMAN DAVID, SILIPHAIVANH PHIENG, FALCONE DANIELLE, ZHOU WEI, MANSOOR UMAR FARUK, TANG SHUYI, KARUNAKARAN GANESH BABU, FEVRIER SALEM, LIPFORD KATHRYN, WHITE CATHERINE, HUANG XIANHAI, RICHARD JUDSON E, KOZLOWSKI JOSEPH, DANIELS MATTHEW H, ANGELES ANGIE R, WILSON KEVIN J, BAKSHI RAMAN KUMAR
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0).