Stable growth hormone compounds resistant to proteolytic degradation

Stable growth hormone compounds resistant to proteolytic degradation

The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.

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Hauptverfasser: THYGESEN PETER, NOERSKOV-LAURITSEN LEIF, CHEN JIANHE, SCHIOEDT CHRISTINE BRUNN, DEMUTH HELLE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator THYGESEN PETER
NOERSKOV-LAURITSEN LEIF
CHEN JIANHE
SCHIOEDT CHRISTINE BRUNN
DEMUTH HELLE
description The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.
format Patent
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Stable growth hormone compounds resistant to proteolytic degradation
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