Stable growth hormone compounds resistant to proteolytic degradation

The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.

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Bibliographische Detailangaben
Hauptverfasser:	THYGESEN PETER, NOERSKOV-LAURITSEN LEIF, CHEN JIANHE, SCHIOEDT CHRISTINE BRUNN, DEMUTH HELLE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.