Deletion mutants of flagellin and methods of use

Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed...

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Bibliographische Detailangaben
Hauptverfasser: LIU GE, BECKER ROBERT S, SONG LANGZHOU, UMLAUF SCOTT W, ZHANG YI, SHAW ALAN R, TUSSEY LYNDA G
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed in the methods in relatively low doses to provide protective immunity to viral infection.