Dual asynchronous and synchronous memory system

Embodiments relate to a dual asynchronous and synchronous memory system. One aspect is a system that includes a memory controller and a memory buffer chip coupled to the memory controller via a synchronous channel. The memory buffer chip includes a memory buffer unit configured to synchronously communicate with the memory controller in a nest domain, and a memory buffer adaptor configured to communicate with at least one memory interface port in a memory domain. The at least one memory interface port is operable to access at least one memory device. A boundary layer is connected to the nest domain and the memory domain, where the boundary layer is configurable to operate in a synchronous transfer mode between the nest and memory domains and to operate in an asynchronous transfer mode between the nest and memory domains.