Method for producing polyprenyl phosphates

Method produces polyprenyl phosphates of formula, where each isoprene unit contains 5 carbon atoms, W is ω-end isoprene, T is trans-isoprene, C is cis-isoprene, S is 2,3-dihydroisoprene, a=0-10, b=0-39, c=0-1, a+b+c=4-40, and X is of formula OPO3MM′, wherein M and M′ are identical or different and a...

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1. Verfasser: DANILOV LEONID LEONIDOVICH
Format: Patent
Sprache:eng
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Zusammenfassung:Method produces polyprenyl phosphates of formula, where each isoprene unit contains 5 carbon atoms, W is ω-end isoprene, T is trans-isoprene, C is cis-isoprene, S is 2,3-dihydroisoprene, a=0-10, b=0-39, c=0-1, a+b+c=4-40, and X is of formula OPO3MM′, wherein M and M′ are identical or different and are a hydrogen cation or monovalent inorganic or organic cation, or M and M′ together are divalent inorganic or organic cation, the phosphorylation of the relevant polyprenol or a mixture of oligomer homologues, where X is hydroxyl group, using a substituted ammonium salt of phosphoric acid in presence of condensing agent, is carried out in a medium of first aprotic organic solvent; and a polyprenyl phosphate of mono- or disubstituted salts thereof with monovalent cations or in form of salts thereof with divalent cations is isolated by extraction and precipitation.