Serine/threonine kinase inhibitors

Compounds having the formula I wherein Z, Z1 Z2 Z3, R3a, R3b and Rb and as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DEMEESE JASON, MOHR PETER J, KOLAKOWSKI GABRIELLE R, GARREY RUSTAM, GAUDINO JOHN J, BOYD STEVEN, WENGLOWSKY STEVEN MARK, THOMAS ALLEN A, BLAKE JAMES F, WALLACE ELI, KAUS ROBERT J, REN LI, SCHWARZ JACOB, MARLOW ALLISON L, CHEN HUIFEN, CHICARELLI MARK JOSEPH, SIEDEM CHRISTOPHER S
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Compounds having the formula I wherein Z, Z1 Z2 Z3, R3a, R3b and Rb and as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.