Method for the preparation of high-purity pharmaceutical intermediates

Method for the preparation of high-purity pharmaceutical intermediates

The present invention is related to intermediates useful in the preparation of pharmaceutically acceptable salts of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparation...

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Bibliographische Detailangaben
Hauptverfasser: MOROVJAN GYORGY, BARTHA FERENC LORANT, KOVANYINE LAX GYORGYI, RUZSICS GYORGY, VOLK BALAZS, BAGYINSZKI GABOR, IMRE JANOS, KRASZNAI GYORGY, NAGY KALMAN, SIPOS EVA, BARKOCZY JOZSEF, KESZTHELYI ADRIENN, SIMIG GYULA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is related to intermediates useful in the preparation of pharmaceutically acceptable salts of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparation thereof and use thereof.