Cysteine cross-linked structural peptides

Cysteine cross-linked structural peptides

Compositions and methods are provided using fusion peptides comprising at least one multi-functional solubility tag having an effective number of cross-linkable cysteines residues. The multi-functional peptidic solubility tags facilitate efficient fusion peptide production, easier downstream process...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GRUBER TANJA MARIA, FAHNESTOCK STEPHEN R, SOLOMON LINDA JANE, FOSSER KARI A, ROUVIERE PIERRE E
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:Compositions and methods are provided using fusion peptides comprising at least one multi-functional solubility tag having an effective number of cross-linkable cysteines residues. The multi-functional peptidic solubility tags facilitate efficient fusion peptide production, easier downstream processing of the fusion peptide, and provide functional surface properties when coupled to a target material while the cross-linkable cysteines provide enhanced durability when binding the fusion peptide to a target material.