Progesterone receptor antagonists

The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of the formula I with a progesterone antagonizing effect and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and also their use for producing medicaments for th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROTGERI ANDREA, BONE WILHELM, HUWE CHRISTOPH, KLAR ULRICH, MÖLLER CARSTEN, SCHWEDE WOLFGANG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of the formula I with a progesterone antagonizing effect and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and also their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular of uterus fibroids (myomas, uterine leiomyomas), endometriosis, heavy menstrual bleeding, meningiomas, hormone-dependent breast cancers and troubles associated with the menopause or for monitoring fertility and emergency contraception.