Assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Methods and system for determination of an anti- antibody (anti-AB) in vitro in a sample from a patient treated with a therapeutic monoclonal antibody (TmAB). Also, methods and systems for the determination of antigen specific antibodies of a particular immunoglobulin class and for the identificatio...

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Hauptverfasser:	GRUNERT VEIT PETER, ROTHFUSS MATTHIAS, UPMEIER BARBARA, KLAUSE URSULA, KUBALEC PAVEL
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMBINATORIAL CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING METALLURGY PHYSICS TESTING
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Beschreibung
Zusammenfassung:	Methods and system for determination of an anti- antibody (anti-AB) in vitro in a sample from a patient treated with a therapeutic monoclonal antibody (TmAB). Also, methods and systems for the determination of antigen specific antibodies of a particular immunoglobulin class and for the identification of a patient who is at risk of developing an adverse drug reaction (ADR) during treatment with a TmAB.