Polymorphs of N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)

Polymorphs of N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)

At least 70% by weight of Compound 1 is the single crystalline form, Form A, Form C, or Form D, of the compound. A pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent, and compound 1, wherein at least 70% by weight of the compound is the single crystalline form, For...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DZIEWISZEK JOANNA, CHOI JUN Y, KOSTIK ELENA, SUN LIJUN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:At least 70% by weight of Compound 1 is the single crystalline form, Form A, Form C, or Form D, of the compound. A pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent, and compound 1, wherein at least 70% by weight of the compound is the single crystalline form, Form A, Form C, or Form D, of the compound. A method of treating a subject with cancer comprises administering to the subject an effective amount of compound 1 or the pharmaceutical composition.