Cyclic CRF antagonist peptides

Cyclic CRF antagonist peptides having improved properties of "drugability". The peptides are 33 residues in length with a lactam bond between the residues in position 22 and 25; however, they may be N-terminally shortened by up to 3 residues.

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Bibliographische Detailangaben
1. Verfasser: RIVIER JEAN E. F
Format: Patent
Sprache:eng
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Zusammenfassung:Cyclic CRF antagonist peptides having improved properties of "drugability". The peptides are 33 residues in length with a lactam bond between the residues in position 22 and 25; however, they may be N-terminally shortened by up to 3 residues.