1,3-oxazolidine-2-one-like compound, preparation method and uses thereof

1,3-oxazolidine-2-one-like compound, preparation method and uses thereof

This invention provides 1,3-oxazolidin-2-one compounds of formula I and their salts, their preparation methods, and use in the preparation of linezolid racemate and its optical isomer, which are used as oxazolidinone antibacterial agents. In the formula, R is H, hydroxyl, halogen, C1-C12 alkyl, C1-C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DENG YONG, SAN ZHI-PEI, WANG SI-QING, CHEN ZAI-XIN, JIANG LONG, ZHANG HUI, XIA ZHENG-JUN, ZHANG MING-GUANG, MAO BAI-YANG, WANG MING-LIN, LIN SONG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention provides 1,3-oxazolidin-2-one compounds of formula I and their salts, their preparation methods, and use in the preparation of linezolid racemate and its optical isomer, which are used as oxazolidinone antibacterial agents. In the formula, R is H, hydroxyl, halogen, C1-C12 alkyl, C1-C12 alkoxy, nitro and carboxyl; and R can be placed at any position on the benzene rings; and the compound is a racemate or an optical isomer.