Macrocyclic serine protease inhibitors

Macrocyclic serine protease inhibitors

Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.

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Bibliographische Detailangaben
Hauptverfasser: LEROY FREDERIC, MEILLON JEANRISTOPHE, CONVARD THIERRY, DEROCK MICHEL, ALEXANDRE FRANCOIS-RENE, PARSY CHRISTOPHE CLAUDE, SURLERAUX DOMINIQUE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.