Carbamoylphosphonates as inhibitors and uses thereof

The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP.

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Bibliographische Detailangaben
Hauptverfasser: HOFFMAN AMNON, BREUER ELI, AINELLY VEERENDHAR, REICH REUVEN, FRANT JULIA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP.