Method of fitting pouch in tissue retrieval device

A tissue retrieval device includes a tubular member, an expandable member, and a tissue retrieval bag. The introducer tube is sized to be inserted into a patient through a trocar. The bag may be selectively opened by the expandable member within the patient. The bag may receive a tissue specimen and be withdrawn from the patient. The bag may be manipulated for packing within the tubular member in a variety of ways. Manipulation of the bag may include folding the bag about axes that are perpendicular to or parallel to the tubular member; rolling the bag about axes that are perpendicular to or parallel to the tubular member; or wrapping the bag about the expandable member, wrapping the bag about a rod, or twisting the bag at a position distal to the expandable member. The tubular member may comprise an environmentally responsive capsule.