TGFP-CAP peptide and its uses

The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF- 1 (transforming growth factor- 1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF- 1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is repres...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SONG SANG SU, KIM YOUNG DEUG, CHO KYOUNG MI, CHUNG YONG-JI, CHOI JUN YOUNG, KIM JIN SEUK, KIM EUN MI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF- 1 (transforming growth factor- 1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF- 1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF- 1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics.