Medical device applications of nanostructured surfaces

This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOCK LAWRENCE A, SAHI VIJENDRA, NIU CHUNMING, HARDEV VEERAL D, DUBROW ROBERT S, DANIELS R. HUGH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.