Method of forming an aerosol for inhalation delivery

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein...

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Bibliographische Detailangaben
Hauptverfasser: MYERS DANIEL J, RABINOWITZ JOSHUA D, HALE RON L, HODGES CRAIG C, MUFSON DANIEL, LLOYD PETER M, WENSLEY MARTIN J, MCKINNEY JEFFREY A, QUINTANA REYNALDO J, ROGERS DANIEL D, SONG SOONHO
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.