Methods of making L-ornithine phenyl acetate

Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, inter-mixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt in situ. The present application also relates to various compos...

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Bibliographische Detailangaben
Hauptverfasser: BEHLING JIM, WATT STEPHEN WILLIAM, ANDERSON KEITH H, FIGINI ATTILIA, DOUGAN CHRISTINE HENDERSON, MANINI PETER
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, inter-mixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt in situ. The present application also relates to various compositions obtained from these processes, including crystalline forms.