System and method for optical biopsy tissue characterization

A method for classifying a tissue sample of a biopsy specimen into one of a plurality of classes is presented. The method includes receiving a light from at least one location of the tissue sample including a plurality of chromophores, wherein the received light comprises at least one of an attenuat...

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Hauptverfasser: DYLOV DMITRY VLADIMIROVICH, SOLOMON STEPHEN B, PATIL ABHIJIT VISHWAS, YAZDANFAR SIAVASH, LANGOJU RAJESH VEERA VENKATA LAKSHMI, DASARATHA SRIDHAR, SUBRAHMANIAM VIGNESH THIRUKAZHUKUNDRAM
Format: Patent
Sprache:eng
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Zusammenfassung:A method for classifying a tissue sample of a biopsy specimen into one of a plurality of classes is presented. The method includes receiving a light from at least one location of the tissue sample including a plurality of chromophores, wherein the received light comprises at least one of an attenuated illumination light and a re-emitted light. The method further includes processing a spectrum of the received light to determine a feature for each of the chromophores in the at least one location of the tissue sample. In addition, the method includes estimating a Z-score for each of the chromophores based on the determined feature. Also, the method includes classifying the tissue sample into one of the plurality of classes based on the estimated Z-score for each of the chromophores.