Excipient for compressed tablets comprising novel spherical mannitol

[Problem to solve] To provide an excipient for compressed tablets capable of diluting active components in the industries of foodstuffs, medicines, etc. applicable to various tablets like disintegrating agents, troches, etc., largely avoiding the conventional compressing troubles about mannitol like...

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Bibliographische Detailangaben
Hauptverfasser:	IMAOKA MAKI, SATOMI JIN
Format:	Patent
Sprache:	eng
Schlagworte:	GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HUMAN NECESSITIES HYGIENE LAYERED PRODUCTS LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION TECHNICAL SUBJECTS COVERED BY FORMER USPC TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TRANSPORTING
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Beschreibung
Zusammenfassung:	[Problem to solve] To provide an excipient for compressed tablets capable of diluting active components in the industries of foodstuffs, medicines, etc. applicable to various tablets like disintegrating agents, troches, etc., largely avoiding the conventional compressing troubles about mannitol like capping, sticking, etc., thereby assuring a high tablet hardness. [Means to solve the problem] An excipient for compressed tablets characterized in that it comprises spherical particles of crystalline mannitol having an aspect ratio of 1.0 to 1.2 and according to Test A, absorption rate 1 of 25 to 60% and absorption rate 2 of 15 to 40%.